Top Podcasts for Midlife Comedy in 2026

The midlife comedy space keeps producing fresh voices and long-running favorites. This list rounds up 25 of the best, including Wiser Than Me with Julia Louis-Dreyfus, 40ish - Navigating midlife and perimenopause, and Hit Play Not Pause.

Wiser Than Me with Julia Louis-Dreyfus

Julia Louis-Dreyfus returns for Season 4 of her award-winning podcast, Wiser Than Me™. Each week, she has funny, touching, personal conversations w...

Content:
Aging GracefullyAging PositivelyCelebrity GossipComedyCultureMidlife Comedy
+13

Audience:
Empty NestersNewlywedsRetireesStay At Home MomsWomen In Leadership
+3

Goal:
Emotional ResilienceGetting MotivatedUnwinding And LaughingWriting A Book

Style:
Interview

When:
Weekend Deep Dive
40ish - Navigating midlife and perimenopause

Welcome to 40ish, a podcast filled with midlife humour, middle age dilemmas, and candid conversations about hormones and aging! Brought to you by t...

Content:
ComedyLife TransitionsMidlife ReinventionRelationships & DatingWomen EmpowermentMidlife Comedy
+1

Audience:
Women Over 40Working Moms

Goal:
Unwinding And Laughing
Hit Play Not Pause

Perimenopause and menopause hit active women differently. We have a different lifestyle and different goals. And we know our bodies. Whether you ru...

Content:
Midlife ReinventionPerimenopause HealthStrength Training WomenWomens HealthMidlife Comedy

Audience:
Menopause SupportWomen In Their 50SWomen Over 40

When:
Weekend Deep Dive
Older and Wider Podcast

From the writers of the internationally successful Grumpy Old Women, award winning Comedian Jenny Eclair and Producer and Writer Judith Holder deli...

Content:
Midlife Comedy

Audience:
Women Over 40
Postcards From Midlife

Are you living in a hormonal hothouse, feeling a little overwhelmed and in need of some positive, uplifting and comforting guidance on how to lead ...

Content:
Life TransitionsMidlife ReinventionMidlife Comedy

Audience:
Women In Their 50SWomen Over 40
I SHAKE MY HEAD

Get ready to laugh out loud with I Shake My Head, the weekly podcast where best friends Lisa Gibson and Samantha Sperling—partners in crime for ove...

Content:
Midlife Comedy
Two Women Chatting

Welcome to Two Women Chatting - the podcast where midlife gets real, inspiring, and finds the joy in our second chapter. Hosted by broadc...

Content:
Midlife ReinventionMidlife Comedy

Audience:
Empty NestersWomen Over 40
My So-Called (Mid)Life

A weekly humor podcast discussing all things related to midlife, relationships, lifestyle, dating, and surviving menopause, and occasionally some n...

Content:
Midlife Comedy
Baby Boomer Tales

Stories from the good old days and beyond.

Content:
Elder CareNostalgiaMidlife Comedy

Audience:
Retirees
Women in the Middle®: Loving Life After 50 - Midlife Coach Podcast

Women in the Middle® is a podcast for midlife women who are ready to hear some good news about being over 50! Suzy Rosenstein, MA and Master Certif...

Content:
Aging PositivelyCareer ChangeIntimacy After 40Life After 60Life CoachingMidlife Comedy
+2

Audience:
Empty NestersWomen Healers 50+Women In Their 50SWomen Over 40
GenX Stories

GenX Stories is a podcast about how the so-called “Lost Generation” found itself at midlife. Join hosts Eve, Lori, Chris & Courtney every other Wed...

Content:
Midlife Comedy
Half Betty

Podcast founder Andrea Rathborne and the iconic Betty White share the same birth date - January 17th. In 2022, as Betty would have celebrated her 1...

Content:
Midlife ReinventionMidlife Comedy
Magnificent Midlife

Midlife isn't the end of meaningful life, just the end of the first half rehearsal. Listen, laugh, learn and be inspired as Rachel Lankester, autho...

Content:
Life After 60Midlife ReinventionMidlife Comedy

Audience:
Women Healers 50+Women Over 40
Mixing Up Midlife

Mixing Up Midlife is a weekly show for women in their 50's and beyond who want to explore this incredible age by being more adventurous and more cu...

Content:
Midlife Comedy

Audience:
Empty Nesters
How Do You Reinvent Yourself in Midlife? | Heavens to Betsy Podcast with Betsy Ronel

Heavens to Betsy is a midlife advice podcast where host, Betsy Ronel tells it like she sees it. Widowhood, single motherhood, financial chaos-Betsy...

Content:
Midlife Comedy
Midlife Mavericks - Living Life Happy, Healthy, Sexy & Strong

Midlife Mavericks is for women who are committed to living their best life in their 50's and beyond - confidently, abundantly and joyfully! Join mo...

Content:
Midlife Comedy
Pause To Go Podcast: What You Need to Know About Menopause and Midlife Transitions

On Pause to Go, Bree Luck walks you through life’s sticky spots — from Middle school through Menopause -- so that you can turn life’s Transitions i...

Content:
Midlife Comedy
Positively Midlife Podcast

Ellen and Tish, college friends now in their 50s, take on midlife with a big dose of reality, humor, and fun. They cover diverse topics including f...

Content:
Midlife Comedy
The Taming Crazy Podcast: Views from Midlife!

Join Alicya, Deb, and Sue as they share the ups, the downs and everything in between on being a midlife woman in today's world. It's like sitting d...

Content:
Midlife Comedy
Midlife Humor Gurus

Content:
Midlife Comedy
Funny Over 50

Funny is funny, at any age. Too old for SNL, late-night likes to give young comics a chance. These hilarious people are older but with age they got...

Content:
Midlife Comedy
Mid-Life Conversations

Two good friends who talk about mental health, life, random thoughts, and funny situations

Content:
Midlife Comedy
Sideline Sisters

Welcome to Sideline Sisters, where the women of Winsidr are taking the lead. Jasmine Harper and Candace Pedraza break down the latest moves, trendi...

Content:
Midlife Comedy
Funny Over 40: Exceptional & Exhausted

A podcast inspired by the comedy show Funny over 40: Exceptional & Exhausted, a groundbreaking, brilliantly funny and undeniably entertaining c...

Content:
Midlife Comedy
"Oldish" - Midlife Unscripted

Content:
Midlife Comedy

Audience:
Empty Nesters