The mature themes space keeps producing fresh voices and long-running favorites. This list rounds up 58 of the best, including My Favorite Murder with Karen Kilgariff and Georgia Hardstark, The Ezra Klein Show, and Call Her Daddy.

  1. Call Her Daddy
    Call Her Daddy
    The most-listened to podcast by women, Alex Cooper’s Call Her Daddy has been creating conversation since 2018. From deep, honest discussions to lau...
  2. Sword and Scale
    Sword and Scale
    Sword and Scale is a weekly true crime podcast covering the dark underworld of crime and the criminal justice system’s response to it. The first ep...
  3. Wiser Than Me with Julia Louis-Dreyfus
    Wiser Than Me with Julia Louis-Dreyfus
    Julia Louis-Dreyfus returns for Season 4 of her award-winning podcast, Wiser Than Me™. Each week, she has funny, touching, personal conversations w...
  4. All There Is with Anderson Cooper
    All There Is with Anderson Cooper
    Grief can feel so lonely but talking about it and listening to others share their experiences helps. In all new episodes of this award-winning podc...
  5. My Dad Wrote A Porno
    My Dad Wrote A Porno
    Imagine if your Dad wrote a dirty book. Most people would try to ignore it and pretend it had never happened - but not Jamie Morton. Instead, he's ...
  6. Sex With Emily
    Sex With Emily
    Dr. Emily Morse shares her expertise on sex, relationships and everything in between! Submit your questions to Emily at sexwithemily.com/ask-emily....
  7. Savage Lovecast
    Savage Lovecast
    Dan Savage, America's only advice columnist, answers your sex and relationship questions and yaps about politics. To record a question for Dan to b...
  8. Ear Hustle
    Ear Hustle
    Ear Hustle is prison slang for eavesdropping, and that’s what listening to the show feels like: a raw, often funny, and always surprising peek into...
  9. The Amelia Project
    The Amelia Project
    The Amelia Project is a secret agency that fakes its clients' deaths, then lets them reappear with a brand new identity! A black comedy full of sec...
  10. RISK!
    RISK!
    If you like The Moth, This American Life or Snap Judgment, take a walk on the wilder side with RISK! Your colorful host Kevin Allison (of the legen...
  11. The Psychology Podcast
    The Psychology Podcast
    In each episode, we talk with inspiring scientists, thinkers, and other self-actualized individuals who will give you a greater understanding of yo...
  12. Shameless Sex
    Shameless Sex
    Amy is a Sex and Relationship Coach and Sex Educator with a passion for promoting unabashed, pleasure-focused sexuality education. April is a motiv...
  13. Pillow Talks
    Pillow Talks
    Meet Vanessa and Xander Marin, your new BFF couple friends! She’s a sex therapist with 20 years of experience and he’s a regular dude. Together the...
  14. The Partially Examined Life Philosophy Podcast
    The Partially Examined Life Philosophy Podcast
    The Partially Examined Life is a podcast by some guys who were at one point set on doing philosophy for a living but then thought better of it. Eac...
  15. Holly Randall Unfiltered
    Holly Randall Unfiltered
    HRU is a podcast series that sheds light on those working in the adult industry, and explores all topics of sex with authors, educators, and advoca...
  16. The White Vault
    The White Vault
    Explore the far reaches of the world’s horrors in the audio drama podcast The White Vault. Follow the collected records of a repair team sent to Ou...
  17. Next Question with Katie Couric
    Next Question with Katie Couric
    Tired of political headlines that feel like déjà vu? Wondering if you actually need to care about every controversy? This season, Kat...
  18. Second Life
    Second Life
    Hosted by Who What Wear co-founder Hillary Kerr, Second Life spotlights successful women who have made major career changes. Guests share...
  19. The Curious Girl Diaries
    The Curious Girl Diaries
    Hi I'm Layla London. I'm just the girl next door who recently decided to explore her sexuality. After a 3.5 year, self imposed, dry spell I woke up...
    Content:
    Mature Themes
  20. The Hilarious World of Depression
    The Hilarious World of Depression
    The groundbreaking, award-winning mental health podcast is under new ownership after six years ago. Old ownership, really, since it's now run by or...
  21. Two Dykes And A Mic
    Two Dykes And A Mic
    Become a Paid Subscriber: https://anchor.fm/two-dykes-and-a-mic/subscribe ”Two Dykes and a Mic” is a weekly queer podcast dedicated to sex positivi...
  22. Guys We F****d
    Guys We F****d
    Hailed as changing the way society thinks about female sexuality, Guys We Fucked continues to pave the way toward a healthier outlook on sex. Hoste...
  23. Weekly Spooky | Scary Stories for Halloween
    Weekly Spooky | Scary Stories for Halloween
    Weekly Spooky is your year-round Halloween podcast for scary stories: original horror fiction, urban legends, haunted places, cryptids and dark fol...
  24. Griefcast
    Griefcast
    My goal right from the beginning was that I wanted it to be a podcast that, when it stopped, you didn’t feel worse,” says Cariad Lloyd, host of Gri...
  25. The Hook Up
    The Hook Up
    The Hook Up is about love, sex and relationships. We answer your questions, learn things together, cry over heartbreak and normalise shit. Every Tu...
    Content:
  26. Come Curious
    Come Curious
    Home of the world's most OPEN, HONEST & EXPLICIT conversations! You’ll be hearing all of our juicy sex stories, getting professional sex advice fro...
  27. Down N Dirty Sexy Hot Adult Stories from the Street
    Down N Dirty Sexy Hot Adult Stories from the Street
    HOT SEXY STORIES designed to GET YOU OFF. This is audio sex at it's finest. Get your tool for play too, use offer code DIRTY50 for 50 percent OFF, ...
    Content:
    Mature Themes
  28. Hi-Phi Nation
    Hi-Phi Nation
    Hi-Phi Nation is philosophy in story-form, integrating narrative journalism with big ideas. We look at stories from everyday life, law, science, po...
  29. Good Mourning
    Good Mourning
    Good Mourning shines a light on what loss is really like with honesty, hope and humour. Hosts Sally Douglas and Imogen Carn are two mates who ...
  30. The Gray Area
    The Gray Area
    Welcome to The Gray Area Podcast! Follow the atrocious takes from Lowfi (Ruben) and JAE (Jorge) on current events, music, sports, and entertainment...
  31. Adult Content: For Adults, By Adults
    Adult Content: For Adults, By Adults
    They're not doctors, they're no sex therapists. They are just two friends who are so well-experienced in dating, love and sex ... especially sex! L...
    Content:
    Explicit ContentMature Themes
  32. Life After Launch: Tools for coping with the empty nest, navigating midlife transitions, and parenting adult children.
    Life After Launch: Tools for coping with the empty nest, navigating midlife transitions, and parenting adult children.
    Your life isn’t over because the kids are grown, it’s just getting started. Life After Launch is the podcast that helps you take back your time, re...
    Content:
    Audience:
  33. Message in the Middle: Midlife Women, Reinvention & Personal Growth
    Message in the Middle: Midlife Women, Reinvention & Personal Growth
    Message in the Middle is a podcast for women navigating the challenges, transitions, and reinventions that often come with midlife. Hosted by ...
  34. Final Days On Earth with Claire St. Amant
    Final Days On Earth with Claire St. Amant
    Greg Williams was a successful tech entrepreneur living a quiet life with his family in a Fort Worth suburb. Until one night in 2011, when his whol...
  35. MILF Podcast - Moms I'd Like to Follow
    MILF Podcast - Moms I'd Like to Follow
    Jennifer Tracy interviews moms about motherhood, entrepreneurship, sexuality and everything in between.
    Content:
    Mature Themes
  36. End of Life Conversations: Normalizing Talk About Death, Dying, and Grief
    End of Life Conversations: Normalizing Talk About Death, Dying, and Grief
    Death touches us all, and yet our culture rarely makes space to talk about it openly. Why is it so hard to have honest conversations about death, d...
  37. Death in the Afternoon
    Death in the Afternoon
    Welcome to your mortality, humans! Death in the Afternoon dispels myths about death and dead bodies, dives into history and dark tales you've never...
    Content:
  38. You, Me and the Big C: Putting the can in cancer
    You, Me and the Big C: Putting the can in cancer
    The coolest club you never want to be a part of...The team on the You, Me & the Big C podcast are your BFF's, your sisters, brothers, fathers a...
    Content:
    Mature Themes
  39. Empty Nest Era
    Empty Nest Era
    Empty Nest Era is the go-to podcast for parents navigating the emotional rollercoaster of the empty nest transition. Hosted by Jamie Chin, Licensed...
    Content:
    Audience:
  40. Death & Disco
    Death & Disco
    Death & Disco is the podcast where we explore how truly embracing death can lead to a more meaningful, magical and radically alive life. Host Emily...
    Content:
    Mature Themes
  41. Hello Prime Life
    Hello Prime Life
    Do you feel stuck in the messiness of midlife? Unseen, unsettled, uninspired, un-everything?Good - because that’s exactly who this show is for.Hell...
    Content:
  42. Kinky Katie's World
    Kinky Katie's World
    Juvenile adult vulgarity at it’s finest! Sex, kink, fetish, BDSM and porn by lifestylers. Hosted by Kinky Katie, lifestyle fetishist, feature and a...
    Content:
  43. Wakers: An Audio Drama
    Wakers: An Audio Drama
    In this grimly humorous audio drama, the afterlife isn’t as restful as you’d hope. When corpses are brought back to life with a little bit of love ...
    Content:
    Mature Themes
  44. Big Sexy Chat Podcast
    Big Sexy Chat Podcast
    Big Sexy Chat is a bold, unfiltered podcast exploring fatness, pleasure, identity, and the realities of living in a body the world wasn’t built for...
    Content:
  45. Talking Taboo with Tara: The Unfiltered Truth
    Talking Taboo with Tara: The Unfiltered Truth
    Talking Taboo with Tara: The Unfiltered Truth  Join Tara as she breaks down the barriers of today's taboo topics and discover the unfiltered t...
    Content:
  46. Mortality Matters: Meaning & Death
    Mortality Matters: Meaning & Death
    A philosopher teaches research into a microphone on the meaning of life and the philosophy of death. Each episode focuses on one article or book ch...
    Content:
    Mature Themes
  47. PacinGuy After Dark
    PacinGuy After Dark
    18+ Conversations with Ry the PacinGuy. PacinGuy After Dark is where we go deep on intimacy, boundaries, body, and adult strategy. No shame. No flu...
    Content:
    Explicit ContentMature Themes
  48. Let's Tawk with Jaime Primak Sullivan
    Let's Tawk with Jaime Primak Sullivan
    Jersey Belle Jaime Primak Sullivan wants to tawk, not talk. The writer and producer behind the Cawfee Tawk Facebook series is back for a hilarious ...
    Content:
    Mature Themes
  49. Consummate Professionals
    Consummate Professionals
    'Consummate Professionals' is a new audio sitcom (scripted fiction podcast) set in an independent adult film studio under new management that aims ...
    Content:
    Mature Themes
  50. Mortality Minded
    Mortality Minded
    Mortality Minded explores life, death, and whatever's next through culture, science, personal growth, and more to shed light on this universal yet ...
    Content:
    Mature Themes
  51. In Bed with Strangers: Lifestyle & Swinger Podcast
    In Bed with Strangers: Lifestyle & Swinger Podcast
    Welcome to the In Bed with Strangers Podcast! I am your host, Casey Donatello (along with my husband Jason). This a sex positive and alternative li...
    Content:
    Mature Themes